Oral isotretinoin and sacroiliitis: causal link or coincidence? Discussion points emerging from a case-based review.

Abstract

Isotretinoin is a retinoid derivative drug used in acne vulgaris treatment. Sacroiliitis has been reported as an uncommon adverse effect following isotretinoin treatment. We report a 30-year-old male patient who developed sacroiliitis after isotretinoin use. Stopping treatment with isotretinoin resulted in a complete disappearance of inflammatory back pain. A literature search was performed to assess the relevance of this association in everyday clinical practice, and to discuss whether the link between isotretinoin and sacroiliitis is causal or coincidental.

• Authors: Betül Sargin, Ciro Manzo
• Journal: Reumatologia (Reumatologia) Vol. 60 Issue 5 Pg. 357-360 ( 2022) ISSN: 0034-6233 [Print] Poland
• PMID: 36381201 (Publication Type: Case Reports)
• Copyright: Copyright: © 2022 Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie.