[One case of rhabdomyolysis caused by acute phoxim poisoning].

Abstract

Patients with organophosphate poisoning usually die from respiratory depression and respiratory failure. The incidence of rhabdomyolysis is relatively low, but the mortality rate is extremely high once it occurs. In this paper, the treatment of a patient with acute phoxim poisoning was analyzed. The patient developed severe rhabdomyolysis syndrome on the 3rd day of treatment, the creatine kinase exceeded the normal value by more than 300 times (up to 103510.65 U/L) , and renal failure occurred. Clinical treatment included active detoxification, blood purification, organ support, and internal environment maintenance. The patient's rhabdomyolysis continued, and the condition worsened. Finally, the family gave up the treatment and the patient died. It is suggested that attention should be paid to the occurrence of rhabdomyolysis syndrome during the treatment of organophosphorus poisoning, and timely blood purification technology may be the key to treatment.

• Authors: J N Wang, C Wang, J Wang, Y X Song, Y P He, Z X Lu
• Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases (Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi) Vol. 40 Issue 10 Pg. 782-784 (Oct 20 2022) ISSN: 1001-9391 [Print] China
• PMID: 36348563 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• phoxim
• Organothiophosphorus Compounds
• Creatine Kinase

Topics

• Humans
• Rhabdomyolysis (chemically induced)
• Organothiophosphorus Compounds
• Creatine Kinase
• Incidence
• Acute Kidney Injury