Eosinophilic cystitis mimicking hemorrhagic cystitis in relapsed follicular lymphoma.

Abstract

Eosinophilic cystitis (EC) is a rare and non-infectious inflammatory disorder characterized by transmural infiltration of eosinophils in the bladder wall. The diagnosis of EC is made only by the pathophysiological findings. Because the urinary symptoms of EC are quite similar to other urinary tract disorders including hemorrhagic cystitis (HC), it can be misdiagnosed or left undiagnosed. A 49-year-old woman with relapsed and refractory follicular lymphoma presented with sudden-onset gross hematuria after the chemo-immunotherapy. The patient was initially treated as HC with continuous bladder irrigation, resulting in recurrent and refractory hematuria. Corticosteroid dramatically resolved hematuria after the bladder biopsy revealed EC. It is important to suspect EC and perform bladder biopsy in patients with recurrent episodes of hematuria or refractory to conservative treatment for HC.

• Authors: Toshiaki Nagaie, Kazuharu Kamachi, Hiroaki Kitamura, Hiroshi Ureshino, Michiaki Akashi, Kazushige Nishimura, Hiroyuki Meiri, Shinya Kimura, Masaharu Miyahara
• Journal: International cancer conference journal (Int Cancer Conf J) Vol. 11 Issue 4 Pg. 298-301 (Oct 2022) ISSN: 2192-3183 [Electronic] Singapore
• PMID: 36186224 (Publication Type: Case Reports)
• Copyright: © The Author(s) under exclusive licence to The Japan Society of Clinical Oncology 2022.