An immunofluorescence study of pityriasis lichenoides.

Abstract

In a study of 27 patients with pityriasis lichenoides IgM and C3 have been observed on direct immunofluorescence of fresh lesions. Other immunoglobulins and complement components were not observed. Immunofluorescence was seen in 31 (72%) of 43 fresh lesions. It occurred in the walls of superficial dermal vessels and along the dermal-epidermal junction. This pattern of immunofluorescence appears to be characteristic of the disease. Uninvolved skin showed the immunofluorescence less frequently and old scaly lesions none. The concept that pityriasis lichenoides is an immune complex disorder is discussed.

• Authors: R Clayton, G Haffenden
• Journal: The British journal of dermatology (Br J Dermatol) Vol. 99 Issue 5 Pg. 491-3 (Nov 1978) ISSN: 0007-0963 [Print] England
• PMID: 361062 (Publication Type: Journal Article)

Chemical References

• Complement C3
• Immunoglobulin M
• Immunoglobulins
• Complement System Proteins

Topics

• Complement C3 (analysis)
• Complement System Proteins (analysis)
• Fluorescent Antibody Technique
• Humans
• Immunoglobulin M (analysis)
• Immunoglobulins (analysis)
• Pityriasis (immunology)
• Skin (blood supply, immunology)