Platelet-Rich Plasma, an Innovative and Noninvasive Technique for Closure of Tracheoesophageal Fistula After Laryngectomy, Report of 2 Cases.

Abstract

An innovative and noninvasive technique for closure of persistent tracheoesophageal fistula after total laryngectomy is described. In our preliminary study, two patients were included. No clinical and radiological signs of locoregional recurrence prior to treatment were diagnosed. We performed local injections of autologous platelet-rich plasma (PRP) according to our protocol. Complete closure of the fistula was observed in both patients who were able to take normal feeding. No side effects associated with the procedure were observed. These preliminary results are encouraging to consider PRP injection before more invasive surgical techniques in the treatment of persistent tracheoesophageal fistulas after total laryngectomy.

• Authors: Maxime Damien, Celine Leclercq, Younès Steffens, Didier Dequanter, Alexandra Rodriguez
• Journal: Ear, nose, & throat journal (Ear Nose Throat J) Pg. 1455613221124729 (Sep 08 2022) ISSN: 1942-7522 [Electronic] United States
• PMID: 36073838 (Publication Type: Journal Article)