Abstract | BACKGROUND: METHODS: PubMed, PEDro, Medline, and the Cochrane Library were searched for LLLT clinical trials published before October 2021. The methodological quality of randomized trials and the effectiveness of Laser Therapy for BCRL were evaluated. The primary objectives were arm circumference or arm volume, whereas the secondary goals were to assess shoulder mobility and pain severity. RESULTS: Eight clinical trials were analyzed in total. Typically, the included RCTs had good research quality. At four weeks, there was a considerable reduction in arm circumference/volume, and this continued with long-term follow-up. However, no statistically significant change in shoulder mobility or pain severity was seen between the laser and placebo groups at 0-, 1-, 2-, and 3-month short-term follow-up. CONCLUSIONS: The findings of this comprehensive study demonstrated that LLLT ( PBM) was successful in diminishing arm circumference and volume than improving shoulder mobility and pain. Data indicates that laser therapy ( PBM) may be a beneficial treatment option for females with PML. Because of the scarcity of evidence, there is a strong need for well-conducted and longer-duration trials in this field. TRIAL REGISTRATION: Details of the protocol for this systematic review were registered on PROSPERO and can be accessed at www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42022315076 .
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Authors | Dania Mahmood, Ashfaq Ahmad, Faiza Sharif, Syed Asadullah Arslan |
Journal | BMC cancer
(BMC Cancer)
Vol. 22
Issue 1
Pg. 937
(Aug 30 2022)
ISSN: 1471-2407 [Electronic] England |
PMID | 36042421
(Publication Type: Journal Article, Systematic Review)
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Copyright | © 2022. The Author(s). |
Topics |
- Breast Cancer Lymphedema
(radiotherapy)
- Breast Neoplasms
(complications, radiotherapy)
- Female
- Humans
- Low-Level Light Therapy
(adverse effects, methods)
- Lymphedema
(etiology)
- Mastectomy
(adverse effects)
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