Abstract | BACKGROUND: METHODS: Eighty eligible women, stratified as low- or high-risk patients, were included and were randomized for treatment with either closed-incision negative-pressure or adhesive strips by drawing sealed, opaque envelopes. All surgeons were kept blinded for allocation. Primary outcomes were surgical wound dehiscence and surgical-site infection at the abdominal donor site on follow-up after 12 weeks. Secondary outcomes were seroma and hematoma formation. Five patients were excluded from the study because of insufficient exposure to the study treatment ( n = 4) or major protocol deviation ( n = 1). RESULTS: A total of 75 women, low-risk ( n = 38) and high-risk ( n = 37), received either closed-incision negative-pressure ( n = 36) or adhesive strips ( n = 39). Patients' demographics did not differ significantly. Donor-site surgical wound dehiscence occurred in 23 patients; the absolute risk reduction was statistically significant (21.6 percent; 95 percent CI, 1.5 to 41.7 percent). No statistically significant differences were found in surgical-site infection or secondary outcomes. CONCLUSION: CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, I.
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Authors | Emmy Muller-Sloof, Erik de Laat, Onur Kenç, Ali Kumaş, Hester Vermeulen, Stefan Hummelink, Dietmar J O Ulrich |
Journal | Plastic and reconstructive surgery
(Plast Reconstr Surg)
Vol. 150
Pg. 38S-47S
(10 01 2022)
ISSN: 1529-4242 [Electronic] United States |
PMID | 35943913
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | Copyright © 2022 by the American Society of Plastic Surgeons. |
Topics |
- Female
- Humans
- Mammaplasty
(adverse effects, methods)
- Negative-Pressure Wound Therapy
(methods)
- Perforator Flap
(adverse effects)
- Postoperative Complications
(epidemiology, etiology, prevention & control)
- Retrospective Studies
- Surgical Wound
(complications)
- Surgical Wound Dehiscence
(epidemiology, etiology, prevention & control)
- Surgical Wound Infection
(epidemiology, etiology, prevention & control)
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