A Case of a Solitary Cortical Tuber with No Other Manifestations of Tuberous Sclerosis Complex Mimicking Focal Cortical Dysplasia Type II with Calcification.

Abstract

Cortical tubers are one of the typical intracranial manifestations of tuberous sclerosis complex (TSC). Multiple cortical tubers are easy to diagnose as TSC; however, a solitary cortical tuber without any other cutaneous or visceral organ manifestations can be confused with other conditions, particularly focal cortical dysplasia. We report a surgical case of refractory epilepsy caused by a solitary cortical tuber mimicking focal cortical dysplasia type II, and describe the radiological, electrophysiological, and histopathological findings of our case.

• Authors: Kakeru Hosomoto, Tatsuya Sasaki, Koji Kawai, Yosuke Okazaki, Yuki Hyodo, Takashi Shibata, Susumu Sasada, Takao Yasuhara, Katsuhiro Kobayashi, Hiroyuki Yanai, Isao Date
• Journal: Acta medica Okayama (Acta Med Okayama) Vol. 76 Issue 3 Pg. 323-328 (Jun 2022) ISSN: 0386-300X [Print] Japan
• PMID: 35790363 (Publication Type: Case Reports)

Topics

• Calcinosis (complications)
• Epilepsy (diagnosis, etiology)
• Humans
• Malformations of Cortical Development (complications, diagnostic imaging)
• Malformations of Cortical Development, Group I (complications, diagnosis)
• Tuberous Sclerosis (diagnosis, pathology, surgery)