Coronary artery disease is the leading cause of death and disability globally. The presentation of Non-
ST segment elevation myocardial infarction (
NSTEMI) is heterogeneous, with different risk levels in terms of death,
infarction and recurrence of
infarction. Current evidence suggests that plasma
glucose level or
hyperglycemia is a mediator of worse prognosis of MI. The objective of the study was to correlate on admission plasma
glucose level in non-diabetic patient with in-hospital outcome of patients after first attack of
NSTEMI. This prospective analytical study was conducted among purposively selected 280 patients with
NSTEMI admitted in coronary care unit of Mymensingh Medical College Hospital during the period of June 2016 to May 2017. Data were collected from the informant by face to face interview, clinical examination and investigations using a pretested semi-structured case record form. Data were analyzed by SPSS. Patients were categorized into two groups; Group A:
NSTEMI with admission plasma
glucose level below 7.8mmol/l, (n=150, Male-110, Female-40). Group B:
NSTEMI with admission plasma
glucose level ≥7.8mmol/l, (n=130, Male-95, Female-35). Group B (n=130) is divided into two subgroups. Subgroup-I:
NSTEMI with
Hyperglycemia (7.8-9.3mmol/l), n = 67 (male 44, female 23), Subgroup-II:
NSTEMI with
Hyperglycemia (≥9.4mmol/l), n = 63 (male 51, female 12). All Patients were non diabetic excluded by HbA₁c. The mean left ventricular ejection fraction (LVEF) of Group B, Subgroup-II was significantly less than that of Subgroup-I (p<0.05). Correlation between LVEF levels and on admission plasma
glucose level showed statistically significant moderate negative correlation, suggesting that the higher was the level of on admission plasma
glucose level; the lower was the LV ejection fraction level in first attack of
NSTEMI patients. Correlation coefficient between
Troponin-I and plasma
glucose level on admission of the study population (r=0.030) suggesting that the higher was the level of admission plasma
glucose level the higher was the
Troponin-I level in first attack of
NSTEMI patients. The more was the plasma
glucose level, less was LVEF, more was the
heart failure and prolonged
hospital stay. The study showed a strong predictor of adverse in-hospital outcome in the various levels of plasma
glucose and
NSTEMI. There was association between the concentration of the plasma
glucose and the extent, severity of disease in the means of mean LVEF, the rate of
heart failure and duration of
hospital stay. The importance of this finding is even clear that RBS is a standard, valuable diagnostic tool for evaluation of severity and prediction of outcome of patients with
NSTEMI.