Abstract | BACKGROUND AND AIMS: Submucosal tunneling endoscopic septum division (STESD) is an endoscopic minimally invasive technique for treating esophageal diverticulum. The objectives of this study were to evaluate the safety and efficacy of STESD and its impact on patients' quality of life. METHODS: This study included consecutive patients who underwent STESD for esophageal diverticulum from April 2016 to August 2020 in 2 centers (Zhongshan Hospital, Fudan University and Tianjin First Central Hospital). Esophagogram and endoscopic examination were performed before STESD and 30 days after STESD. Patients completed the 36-item Short Form survey (SF-36) before STESD and 1 year after surgery. Clinical symptoms were assessed via telehealth every 6 months until August 2021. Costamagna and Eckardt scores were used to evaluate changes in symptoms. RESULTS: Twenty-one patients were included. Mucosal injury 1 to 2 cm below the septum occurred in 2 patients. No severe surgical adverse events were observed. Median duration of follow-up was 39 months (range, 12-63). Total SF-36 scores increased from 118.7 ± 18.6 before STESD to 132.4 ± 9.1 at 1 year after the procedure (P = .007). SF-36 subscales of general health (P = .002), vitality (P = .004), social functioning (P = .030), and mental health (P = .020) improved significantly after STESD. The mean Costamagna score decreased from 3.83 ± 1.33 to 1.67 ± 1.51 (P = .010), whereas the mean Eckardt score decreased from 3.50 ± .90 to 1.25 ± 1.76 (P = .002). One patient developed symptom recurrence at 10 months after STESD. CONCLUSIONS:
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Authors | Dan-Feng Zhang, Wei-Feng Chen, Ye Wang, Mei-Dong Xu, Xiao-Cen Zhang, Ming-Yan Cai, Shi-Yao Chen, Yun-Shi Zhong, Yi-Qun Zhang, Guo-Liang Zhang, Ping-Hong Zhou, Quan-Lin Li |
Journal | Gastrointestinal endoscopy
(Gastrointest Endosc)
Vol. 96
Issue 4
Pg. 612-619.e1
(10 2022)
ISSN: 1097-6779 [Electronic] United States |
PMID | 35679964
(Publication Type: Journal Article, Multicenter Study)
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Copyright | Copyright © 2022 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved. |
Topics |
- Cohort Studies
- Diverticulum, Esophageal
(diagnosis)
- Esophagoscopy
(methods)
- Follow-Up Studies
- Humans
- Quality of Life
- Retrospective Studies
- Treatment Outcome
- Zenker Diverticulum
(surgery)
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