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A comparative study of intravenous labetalol VS intravenous nitroglycerin in the treatment of hypertensive crises.

Abstract
Hypertensive crises is still a major public health problem, causing end organ damage like myocardial infarction, stroke, and renal failure. Labetalol and nitroglycerine are among the two most commonly used medicine to control the blood pressure, but there is no head to head comparison between these two medicines. This was a prospective randomized non-blinded study which included 50 patients of hypertensive crises, out which 25 patients received intravenous labetalol and 25 patients received intravenous nitroglycerine. We found that labetalol controlled the blood pressure more rapidly in comparison to nitroglycerine, without causing any extra side effect.
AuthorsMohammad Azharuddin Malik, Rehan Ahmad, Mujahid Beg, Rizwan Ahmad
JournalIndian heart journal (Indian Heart J) 2022 Jul-Aug Vol. 74 Issue 4 Pg. 332-334 ISSN: 2213-3763 [Electronic] India
PMID35667400 (Publication Type: Journal Article, Randomized Controlled Trial)
CopyrightCopyright © 2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. All rights reserved.
Chemical References
  • Antihypertensive Agents
  • Nitroglycerin
  • Labetalol
Topics
  • Antihypertensive Agents (therapeutic use)
  • Blood Pressure
  • Humans
  • Hypertension (drug therapy)
  • Labetalol (pharmacology, therapeutic use)
  • Nitroglycerin (pharmacology)
  • Prospective Studies

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