HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Post-dural puncture headache diagnosis and management.

Abstract
Epidural analgesia, commonly used to alleviate labor pain, is not without complication. The most common complication associated with labor epidural analgesia (LEA) is Unintentional Dural Puncture (UDP), where many professionals go on to develop a Post Dural Puncture Headache (PDPH). Spinal anesthesia can also result in PDPH. Other complications of dural puncture necessitating further treatment include hospital readmission, persistent headache, persistent backache, cerebral venous thrombosis, subdural hematoma, postpartum depression, post-traumatic stress disorder, and decreased maternal breastfeeding. In this article, we will define and discuss the definition and diagnosis for PDPH, the pathophysiology of PDPH, PDPH treatment options including conservative therapy, pharmacologic therapy, and invasive procedural measures including the therapeutic epidural blood patch, prophylactic epidural blood patch, intrathecal catheter placement after UDP, and potential new therapies.
AuthorsManuel C Vallejo, Mark I Zakowski
JournalBest practice & research. Clinical anaesthesiology (Best Pract Res Clin Anaesthesiol) Vol. 36 Issue 1 Pg. 179-189 (May 2022) ISSN: 1878-1608 [Electronic] Netherlands
PMID35659954 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2022 Elsevier Ltd. All rights reserved.
Chemical References
  • Uridine Diphosphate
Topics
  • Anesthesia, Obstetrical (adverse effects)
  • Anesthesia, Spinal (adverse effects)
  • Blood Patch, Epidural (adverse effects)
  • Female
  • Humans
  • Post-Dural Puncture Headache (diagnosis, etiology, therapy)
  • Pregnancy
  • Uridine Diphosphate

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: