Abstract | OBJECTIVE: METHODS:
Mild traumatic brain injury was induced with a weight drop method. Periorbital and hindpaw cutaneous allodynia were measured for 14 days. Mice were then exposed to bright light stress and allodynia was reassessed. OnabotulinumtoxinA (0.5 U) was injected subcutaneously over the cranial sutures at different post-injury time points. RESULTS: CONCLUSION:
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Authors | Edita Navratilova, Janice Oyarzo, Trent Anderson, Ron S Broide, Sudhakar R Subramaniam, Edwin J Vazquez-Cintron, Mitchell F Brin, Todd J Schwedt, David W Dodick, Frank Porreca |
Journal | Cephalalgia : an international journal of headache
(Cephalalgia)
Vol. 42
Issue 11-12
Pg. 1194-1206
(10 2022)
ISSN: 1468-2982 [Electronic] England |
PMID | 35546268
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Botulinum Toxins, Type A
(therapeutic use)
- Brain Concussion
(drug therapy)
- Headache
(drug therapy)
- Hyperalgesia
(drug therapy, etiology)
- Mice
- Pain
(drug therapy)
- Post-Traumatic Headache
(drug therapy, etiology)
- Tension-Type Headache
(drug therapy)
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