Abstract | BACKGROUND: METHODS: A prospective, double blind study was conducted, and 90 American Society of Anesthesiologists (ASA) I and II patients of either gender between 18-65 years undergoing laparoscopic surgeries under general anesthesia were randomized into three groups. (1) Group N ( n = 30) received dexmedetomidine nebulization 1 mcg/kg in 3 mL of 0.9% saline 15 minutes before induction and 10 mL of intravenous 0.9% saline over 10 minutes at the time of induction of anesthesia. (2) Group I ( n = 30) received 0.9% saline nebulization 3 mL and intravenous dexmedetomidine 1 mcg/kg in 10 mL of 0.9% saline. (3) Group F ( n = 30) received 0.9% saline nebulization 3 mL and intravenous fentanyl 2 mcg/kg in 10mL of 0.9% saline. Heart rate, blood pressure, propofol requirement, and opioid consumption were monitored throughout surgery and for 1 hour in post-operative period. Statistical analysis was done by using analysis of variance test, chi-square test. P value < 0.05 was considered signifi cant. RESULTS: CONCLUSIONS:
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Authors | Kantharaju Shankar, Srinivasan Rangalakshmi, P Kailash, D Priyanka |
Journal | Asian journal of anesthesiology
(Asian J Anesthesiol)
Vol. 60
Issue 1
Pg. 33-40
(03 01 2022)
ISSN: 2468-824X [Electronic] China (Republic : 1949- ) |
PMID | 35483678
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Analgesics, Opioid
- Saline Solution
- Dexmedetomidine
- Fentanyl
- Propofol
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Topics |
- Analgesics, Opioid
(pharmacology)
- Anesthesia, General
- Dexmedetomidine
(pharmacology)
- Fentanyl
(pharmacology)
- Hemodynamics
- Humans
- Laparoscopy
- Propofol
- Prospective Studies
- Saline Solution
(pharmacology)
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