The effectiveness of portable ultrasound-guided resuscitative endovascular balloon occlusion of the aorta for stopping iliac artery hemorrhage during first aid pre-hospital: a randomized control animal trial.

Abstract

PURPOSE:

This study aimed at to comparing the effectiveness of portable ultrasound guided REBOA vs. traditional manual extracorporeal compression in stopping iliac artery hemostasis.

METHODS:

Twelve swine were included in this study (treatment group vs. control group, 6:6). A biopsy device was used to create an iliac artery rupture and hemorrhage in each swine. After 30 s of bleeding, the treatment group received REBOA under the guidance of ultrasound, whereas the control group received traditional manual extracorporeal compression. General physiological conditions were recorded at 0 s (baseline, T1), 30 s (initiation of therapies to stop bleeding, T2), 10 min (T3) and 30 min (T4) after bleeding. Intraperitoneal and retroperitoneal hemorrhage and specimens of iliac artery were collected after all swine were euthanized.

RESULTS:

One swine was excluded because of accidental death not related to the experiment; thus, 11 swine were analyzed in this study. The general physiological characteristics of the two groups showed no difference at T1. Hemorrhagic shock occurred in both groups. After the hemostatic procedure was performed, systolic pressure, diastolic pressure and heart rate first increased significantly between T2 and T3, and then became stable between T3 and T4; these indicators in the control group deteriorated over time. The total blood loss in the treatment group (1245.23 ± 190.07 g) was much significantly less than that in the control group (2605.63 ± 291.67 g) with p < 0.001.

CONCLUSIONS:

Performing REBOA under the guidance of portable ultrasound is an effective way to stop bleeding. It suggests a potential alternative method for iliac artery hemostasis in the pre-hospital setting.

• Authors: Yuqing Huang, Haiyan Kou, Yuhao Kong, Xuexia Shan, Shengzheng Wu, Xianghui Chen, Xingxi Lin, Liye Zhang, Faqin Lv, Zhihui Li
• Journal: European journal of trauma and emergency surgery : official publication of the European Trauma Society (Eur J Trauma Emerg Surg) Vol. 48 Issue 4 Pg. 2841-2848 (Aug 2022) ISSN: 1863-9941 [Electronic] Germany
• PMID: 35412061 (Publication Type: Journal Article)
• Copyright: © 2022. The Author(s).

Topics

• Animals
• Aorta
• Balloon Occlusion (methods)
• Disease Models, Animal
• Endovascular Procedures (methods)
• First Aid
• Hemodynamics
• Hemorrhage (etiology, therapy)
• Hemostasis
• Hospitals
• Iliac Artery
• Resuscitation (methods)
• Shock, Hemorrhagic (therapy)
• Swine
• Ultrasonography, Interventional (adverse effects)