Myelin oligodendrocyte glycoprotein (MOG) antibody disease most commonly presents with
optic neuritis, though
myelitis is also possible. It is rare in the post-infectious and particularly post-COVID-19 setting. Case Presentation. We present the case of a 57-year-old man who tested positive for
COVID-19 and experienced respiratory symptoms that completely resolved within one week. About 3 weeks after testing positive, he began experiencing acute onset
anuria, followed by lower extremity
paresthesia and
paraparesis, which progressed to bilateral lower extremity
paraplegia, complete loss of sensation of
pain, temperature, vibration, and proprioception, and a T4 sensory level. He was initially diagnosed with and treated for
acute inflammatory demyelinating polyradiculoneuropathy (AIDP), after which he made minimal clinical improvement. The diagnosis was shifted to longitudinally extensive
transverse myelitis, and his CSF tested positive for MOG
antibodies. He is being treated with a
steroid regimen and extensive outpatient
physical therapy.
Conclusion: