Pompholyx as a side effect of intravenous immunoglobulin (IVIg).

Abstract

Intravenous immunoglobulin (IVIg) is increasingly used across multiple specialties for the treatment of inflammatory and autoimmune diseases. Cutaneous reactions to IVIg are generally minor. Pompholyx is a common eruption of small vesicles on the palms, soles, and/or lateral aspects of the fingers. It has a multifactorial aetiology but is rarely attributed to being a drug-related side effect. We describe a 43-year-old woman presenting with peripheral sensory neuropathy who developed pompholyx eczema on both palms following treatment with IVIg.

• Authors: Claire Doyle, Karen Eustace
• Journal: BMJ case reports (BMJ Case Rep) Vol. 15 Issue 3 (Mar 30 2022) ISSN: 1757-790X [Electronic] England
• PMID: 35354565 (Publication Type: Case Reports, Journal Article)
• Copyright: © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Chemical References

• Immunoglobulins, Intravenous

Topics

• Adult
• Autoimmune Diseases (drug therapy)
• Drug-Related Side Effects and Adverse Reactions
• Eczema, Dyshidrotic (chemically induced, drug therapy)
• Female
• Humans
• Immunoglobulins, Intravenous (adverse effects)
• Peripheral Nervous System Diseases (chemically induced)