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Epidrugs in Amyotrophic Lateral Sclerosis/Frontotemporal Dementia: Contextualizing a Role for Histone Kinase Inhibition in Neurodegenerative Disease.

Abstract
Breakthroughs in understanding the epigenetic mechanisms involved in neurodegenerative disease have highlighted "epidrugs" as a potential avenue for therapeutic development. Here, we expand on the future of epidrugs against neurodegeneration and discuss promising novel targets underexploited thus far: histone kinases.
AuthorsSamantha N Cobos, Mariana P Torrente
JournalACS pharmacology & translational science (ACS Pharmacol Transl Sci) Vol. 5 Issue 2 Pg. 134-137 (Feb 11 2022) ISSN: 2575-9108 [Electronic] United States
PMID35187420 (Publication Type: Journal Article)
Copyright© 2022 American Chemical Society.

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