Effective protection against influenza after vaccination with subunit vaccine.

Abstract

Immunization with an influenza subunit vaccine given in one dose about 1 month to 2 months before onset of an epidemic of influenza afforded from 80% to 90% protection in a double-blind clinical trial which was supported by isolation of virus and serological studies. In the vaccinated group, 20% failed to develop antibodies to the vaccine. Either serology tests or attempted isolation of virus alone would have failed to detect some of the cases.

• Authors: M L Hammond, A A Ferris, S Faine, T McAvan
• Journal: The Medical journal of Australia (Med J Aust) Vol. 1 Issue 6 Pg. 301-3 (Mar 25 1978) ISSN: 0025-729X [Print] Australia
• PMID: 351351 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Antibodies, Viral
• Influenza Vaccines

Topics

• Antibodies, Viral (biosynthesis)
• Clinical Trials as Topic
• Double-Blind Method
• Humans
• Influenza A virus (immunology)
• Influenza Vaccines (therapeutic use)
• Influenza, Human (epidemiology, prevention & control)
• Vaccination