[Results of noxythiolin use in acute peritonitis].

Abstract

The authors present a series of 30 cases of acute supra- and inframesocolic peritonitis which, in addition to the treatment of their organic causes, benefitted from medical treatment by noxythioline, used as a peritoneal lavage, an irrigation with aspiration, or an instillation. A marked amelioration in the postoperative course was noted, particularly in those cases with infra-mesocolic peritonitis, with the absence of adhesions and suppurative collections on reintervention, and a rapid return to negativity of the positive bacteriological investigations performed systematically on the pe ritoneal fluid and on the drainage.

• Authors: G Migliori, F Codinach, A Marsan, J A Inglésakis
• Journal: Annales de l'anesthesiologie francaise (Ann Anesthesiol Fr) Vol. 19 Issue 11-12 Pg. 903-7 ( 1978) ISSN: 0003-4061 [Print] France
• Vernacular Title: Résultats de l'utilisation de la noxythioline au cours des péritonites aiguës.
• PMID: 35069 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Noxythiolin
• Thiourea

Topics

• Acute Disease
• Administration, Topical
• Adolescent
• Adult
• Age Factors
• Aged
• Clinical Trials as Topic
• Drug Tolerance
• France
• Humans
• Middle Aged
• Noxythiolin (administration & dosage)
• Peritoneal Dialysis
• Peritonitis (drug therapy, mortality)
• Therapeutic Irrigation
• Thiourea (analogs & derivatives)