A Rare Cause of Acquired Factor X Deficiency in an 87-Year-Old Female.

Abstract

Factor X deficiency is a rare coagulopathy that can be inherited or acquired. Acquired factor X deficiency has been associated with plasma cell dyscrasias, amyloids, and use of vitamin K antagonists. Of plasma cell dyscrasias, most cases in the literature have been associated with multiple myeloma with or without concomitant AL amyloidosis. Here, we present a rare case of acquired isolated factor X deficiency in an elderly patient with immunoglobulin A (Ig A) monoclonal gammopathy of undetermined significance (MGUS). Herein, we highlight a rare cause of acquired factor X deficiency, and we hope to contribute to the growing literature of plasma cell dyscrasias associated with factor X deficiency.

• Authors: Ayrton Bangolo, Trupti Waykole, Bilal Niazi, Chandini Sajja, Mahabuba Akhter, Bhavna Gupta, Sameh Elias
• Journal: Case reports in hematology (Case Rep Hematol) Vol. 2021 Pg. 1138329 ( 2021) ISSN: 2090-6560 [Print] United States
• PMID: 34840836 (Publication Type: Case Reports)
• Copyright: Copyright © 2021 Ayrton Bangolo et al.