Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3-5 Years in China.

Abstract

BACKGROUND:

Vitamin D deficiency is prevalent globally and there is lack of evidence as to how 25(OH)D2 contributes to vitamin D status. The aim of this study was to describe vitamin D status and to assess the role of vitamin D2, a dietary vitamin D source, against the vitamin D status of children aged 3-5 years in China.

METHODS:

Data were extracted from the Chinese National Nutrition and Health Surveillance (CNNHS) in 2013. The concentration of serum 25(OH)D2 and 25(OH)D3 was measured by using LC-MS/MS.

RESULTS:

A total of 1435 subjects were enrolled and serum 25(OH)D were analyzed. The prevalence of total serum 25(OH)D < 30 nmol/L was 8.9%. Serum 25(OH)D2 was detected in 10.9% of the studied children. After adjusting for confounding factors, total 25(OH)D concentration was 8.48 nmol/L lower and odds ratio of vitamin D deficiency was 4.20 times (OR (95%CI): 4.20 (1.64, 10.77)) in children without 25(OH)D2 than those with 25(OH)D2 detected.

CONCLUSIONS:

Vitamin D deficiency was common among children aged 3-5 years in China. Vitamin D2 may play a role in preventing vitamin D deficiency in Chinese children aged 3-5 years.

• Authors: Xuehong Pang, Zhenyu Yang, Jie Wang, Yifan Duan, Liyun Zhao, Dongmei Yu, Jianqiang Lai
• Journal: Nutrients (Nutrients) Vol. 13 Issue 11 (Nov 19 2021) ISSN: 2072-6643 [Electronic] Switzerland
• PMID: 34836390 (Publication Type: Journal Article)

Chemical References

• 25-Hydroxyvitamin D 2
• Calcifediol

Topics

• 25-Hydroxyvitamin D 2 (blood)
• Calcifediol (blood)
• Child, Preschool
• China (epidemiology)
• Chromatography, Liquid
• Female
• Humans
• Male
• Nutrition Surveys
• Nutritional Status
• Population Surveillance
• Prevalence
• Tandem Mass Spectrometry
• Vitamin D Deficiency (blood, epidemiology)