Abstract | INTRODUCTION/AIMS: METHODS: PNCS amplitude ( avAMP) and latency (avLAT) were compared between patients who required IMV (IMV group) and those who did not (non-IMV group). PNCS were performed in 62 healthy controls and in patients with four different diseases that may require IMV: ALS (n = 56), GBS (n = 72), CIDP (n = 38), and DM (n = 24). RESULTS: The IMV group consisted of 12 patients with ALS, 14 with GBS, 2 with CIDP, and 4 with DM. avAMP was significantly lower in the IMV group with ALS than in the non-IMV group (P < .05), but no significant difference was observed in avLAT. avAMP was significantly lower and avLAT was significantly longer in the IMV group with GBS than in the non-IMV group (both P < .05). Receiver operating characteristic analysis showed that the avAMP cutoff between the IMV and non-IMV groups was 184.3 μV (area under the curve = 0.921; sensitivity, 84.6%; specificity, 88.2%) for ALS and GBS. DISCUSSION: PNCSs may aid in determining whether a patient with ALS or GBS requires IMV.
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Authors | Shinya Narukawa, Keita Ishizuka, Kohei Sugimoto, Kyoichi Nomura |
Journal | Muscle & nerve
(Muscle Nerve)
Vol. 65
Issue 2
Pg. 211-216
(02 2022)
ISSN: 1097-4598 [Electronic] United States |
PMID | 34708432
(Publication Type: Journal Article)
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Copyright | © 2021 Wiley Periodicals LLC. |
Topics |
- Guillain-Barre Syndrome
(therapy)
- Humans
- Neural Conduction
(physiology)
- Neurologic Examination
- Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
- Respiration, Artificial
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