Characterization of Contractile Forces Generated by Stretch Marks Fibroblasts: In Vitro Study.

Abstract

Authors present a study about the contraction forces observed in striae distensae fibroblasts (SMF) in a collagen scaffold. Collagen lattices were used to study the mechanical behavior of SDF within the collagen matrix compared to the lattices produced using the healthy skin derived fibroblasts (NSF). A Forcebox device was used to measure the contractile forces. Striae Rubrae fibroblast's contractile force was by 28% greater than that generated by the NSF and striae albae fibroblasts (P<0.05). Anomalies and especially differences in forces generated by SMF were observed through all our experiments. These findings complete and corroborate the results and information published in our previous studies. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

• Authors: Rosita Pensato, Barbara Hersant, Chiara Pizza, Concetta Errico, Francesco D'Andrea, Umberto Rega, Paolo Persichetti, Jean Paul Meningaud, Simone La Padula
• Journal: Aesthetic plastic surgery (Aesthetic Plast Surg) Vol. 46 Issue 3 Pg. 1504-1506 (06 2022) ISSN: 1432-5241 [Electronic] United States
• PMID: 34608513 (Publication Type: Letter)
• Copyright: © 2021. Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery.

Chemical References

• Collagen

Topics

• Collagen
• Fibroblasts
• Humans
• Muscle Contraction
• Striae Distensae