[Immunogenetic studies in patients with IgM rheumatoid factor negative erosive chronic polyarthritis (c.p.)].

Abstract

40 patients with erosive rheumatoid arthritis (RA), 20 of whom were IgM-negative and 20 IgM-positive, were studied prospectively with regard to their association with HLA-B-CREGs (B5-, B8-, B12-, B16-, B27-CREG). We found a highly significant association of IgM-negative RA patients and B5-CREG-antigens (Chi2 = 28.6; p less than 0.001).

• Authors: H Bröll, G Haberhauer
• Journal: Zeitschrift fur Rheumatologie (Z Rheumatol) 1986 Mar-Apr Vol. 45 Issue 2 Pg. 57-9 ISSN: 0340-1855 [Print] Germany
• Vernacular Title: Immungenetische Untersuchungen bei Patienten mit IgM-Rheumafaktor-negativer erosiver chronischer Polyarthritis (c.P.).
• PMID: 3460283 (Publication Type: English Abstract, Journal Article)

Chemical References

• HLA Antigens
• HLA-B Antigens
• Immunoglobulin M
• Rheumatoid Factor

Topics

• Alleles
• Arthritis, Rheumatoid (genetics, immunology)
• Chromosome Mapping
• Female
• Gene Frequency
• HLA Antigens (genetics)
• HLA-B Antigens
• Humans
• Immunoglobulin M (metabolism)
• Male
• Middle Aged
• Rheumatoid Factor (metabolism)