Addition of intracranial aspiration to balloon guide catheter does not improve outcomes in large vessel occlusion anterior circulation stent retriever based thrombectomy for acute stroke.

Abstract

BACKGROUND:

Balloon guide catheter (BGC) in stent retriever based thrombectomy (BGC+SR) for patients with large vessel occlusion strokes (LVOS) improves outcomes. It is conceivable that the addition of a large bore distal access catheter (DAC) to BGC+SR leads to higher efficacy. We aimed to investigate whether the combined BGC+DAC+SR approach improves angiographic and clinical outcomes compared with BGC+SR alone for thrombectomy in anterior circulation LVOS.

METHODS:

Consecutive patients with anterior circulation LVOS from June 2019 to November 2020 were recruited from the ROSSETTI registry. Demographic, clinical, angiographic, and outcome data were compared between patients treated with BGC+SR alone versus BGC+DAC+SR. The primary outcome was first pass effect (FPE) rate, defined as near complete/complete revascularization (modified Thrombolysis in Cerebral Infarction (mTICI) 2c-3) after single device pass.

RESULTS:

We included 401 patients (BGC+SR alone, 273 (66.6%) patients). Patients treated with BGC+SR alone were older (median age 79 (IQR 68-85) vs 73.5 (65-82) years; p=0.033) and had shorter procedural times (puncture to revascularization 24 (14-46) vs 37 (24.5-63.5) min, p<0.001) than the BGC+DAC+SR group. Both approaches had a similar FPE rate (52% in BGC+SR alone vs 46.9% in BGC+DAC+SR, p=0.337). Although the BGC+SR alone group showed higher rates for final successful reperfusion (mTICI ≥2b (86.8% vs 74.2%, p=0.002) and excellent reperfusion, mTICI ≥2 c (76.2% vs 55.5%, p<0.001)), there were no significant differences in 24 hour National Institutes of Health Stroke Scale score or rates of good functional outcome (modified Rankin Scale score of 0-2) at 3 months across these techniques.

CONCLUSIONS:

Our data showed that addition of distal intracranial aspiration catheters to BGC+SR based thrombectomy in patients with acute anterior circulation LVO did not provide higher rates of FPE or improved clinical outcomes.

• Authors: Jordi Blasco, Josep Puig, Antonio López-Rueda, Pepus Daunis-I-Estadella, Laura Llull, Federico Zarco, Napoleon Macias, Juan Macho, Eva González, Ion Labayen, Pedro Vega, Eduardo Murias, Elvira Jimenez-Gomez, Isabel Bravo Rey, Manuel Moreu, Carlos Pérez-García, Oscar Chirife Chaparro, Sonia Aixut, Mikel Terceño, Mariano Werner, José Manuel Pumar, Yeray Aguilar Tejedor, Jose Carlos Mendez, Sarai Moliner, Raul G Nogueira, Luis San Roman, ROSSETTI Group
• Journal: Journal of neurointerventional surgery (J Neurointerv Surg) Vol. 14 Issue 9 Pg. 863-867 (Sep 2022) ISSN: 1759-8486 [Electronic] England
• PMID: 34452989 (Publication Type: Journal Article)
• Copyright: © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Topics

• Aged
• Brain Ischemia (diagnostic imaging, surgery)
• Catheters
• Cerebral Infarction (etiology)
• Endovascular Procedures (methods)
• Humans
• Retrospective Studies
• Stents (adverse effects)
• Stroke (diagnostic imaging, surgery)
• Thrombectomy (methods)
• Treatment Outcome