Abstract | BACKGROUND:
Phoxim is a widely used organophosphorus pesticide in agriculture. People are paying more and more attention to its toxicity. At present, there is no appropriate way to solve the phoxim poisoning of silkworm, which severely affected the development of sericulture. Fe2+, Cu2+, Rb+ exerted their biological effects through various forms in vivo. METHODS: To evaluate the effect of Fe2+/Cu2+/Rb+ on phoxim poisoning in silkworm, Bombyx mori were treated with fresh mulberry leaves soaked in 2.5 mg/L phoxim for 2 min with 50 mg/L FeCl2, 150 mg/L CuCl2, or 0.5 mg/L RbCl from 5 days of the fifth-instar silkworm. RESULTS: CONCLUSIONS: These results showed that Fe2+, Cu2+, and Rb+ treatments protected the silkworm from phoxim poisoning by directly enhancing the activity of SOD, CAT, and CarE enzymes and reducing oxidative stress, but not dependent on the high expression of CYP genes. The use of Fe2+, Cu2+, and Rb+ to enhance the activity of SOD, CAT, and CarE enzymes may be an underlying effective way to solve phoxim poisoning in the silkworm industry.
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Authors | Jianjun Guo, Xiaoliang Wang, Wenrong Wang, Lingling Jia, Wei Guo, Guohua Wu |
Journal | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
(J Trace Elem Med Biol)
Vol. 68
Pg. 126844
(Dec 2021)
ISSN: 1878-3252 [Electronic] Germany |
PMID | 34425455
(Publication Type: Journal Article)
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Copyright | Copyright © 2021 Elsevier GmbH. All rights reserved. |
Chemical References |
- Insecticides
- Organophosphorus Compounds
- Organothiophosphorus Compounds
- Pesticides
- phoxim
- Superoxide Dismutase
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Topics |
- Animals
- Bombyx
- Insecticides
(toxicity)
- Organophosphorus Compounds
- Organothiophosphorus Compounds
(toxicity)
- Pesticides
- Superoxide Dismutase
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