Ophthalmic artery occlusion following n-butyl cyanoacrylate embolization of an orbital arteriovenous malformation.

Abstract

A 33-year-old pregnant woman presented with six months of right-sided proptosis. Neuroimaging revealed a right orbital arteriovenous malformation arising from the second segment of the ophthalmic artery. As she was 9 weeks pregnant, the decision was made to monitor her closely. Over the following six months, her proptosis progressed, accompanied by decreased visual acuity, afferent pupillary defect, and red desaturation concerning for compressive optic neuropathy. After planned c-section, she underwent embolization with n-butyl cyanoacrylate. Upon awakening after embolization, she had no light perception vision from her right eye and was found to have ophthalmic artery obstruction. She ultimately developed a blind painful right eye and underwent enucleation with histopathology demonstrating glue in the central retinal artery, posterior ciliary arteries, and choroid. This case highlights ophthalmic artery occlusion as a rare complication of orbital arteriovenous malformation embolization and demonstrates correlating histopathological findings, which have not previously been reported.

• Authors: Marissa K Shoji, Ann Q Tran, Wendy W Lee, Sander R Dubovy, Andrea L Kossler
• Journal: Orbit (Amsterdam, Netherlands) (Orbit) Vol. 42 Issue 1 Pg. 87-93 (Feb 2023) ISSN: 1744-5108 [Electronic] England
• PMID: 34365893 (Publication Type: Case Reports, Journal Article)

Chemical References

• Enbucrilate

Topics

• Female
• Humans
• Adult
• Ophthalmic Artery (diagnostic imaging)
• Enbucrilate
• Arteriovenous Malformations (diagnostic imaging, therapy)
• Embolization, Therapeutic (adverse effects, methods)
• Exophthalmos (etiology)
• Retinal Artery Occlusion
• Blindness