Abstract |
The present study is the first systematic review of papers that have performed a full economic evaluation on oral cancer screening strategies using visual oral examination. The review questions were (1) Is screening a cost-effective strategy in oral cancer? (2) What is the most cost-effective strategy among the different screening approaches in oral cancer? The main outcome measure was the incremental cost-effectiveness ratio. The study identifies and reviews seven full economic evaluations. The included studies scored 75%-100% on the methodological appraisal. Majority of the studies reports that oral cancer screening is a cost-effective strategy, especially in an opportunistic setting and high-risk subset of patients. The results were sensitive to cost and effectiveness parameters. Oral cancer screening, though found cost-effective, the uncertainty around these parameters necessitates additional studies that include better estimates in the modeling assessments. The heterogeneity in studies limited comparison and generalization.
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Authors | Krishnakumar Thankappan, Sujha Subramanian, Deepak Balasubramanian, Moni Abraham Kuriakose, Rengaswamy Sankaranarayanan, Subramania Iyer |
Journal | Head & neck
(Head Neck)
Vol. 43
Issue 11
Pg. 3646-3661
(11 2021)
ISSN: 1097-0347 [Electronic] United States |
PMID | 34260118
(Publication Type: Journal Article, Review, Systematic Review)
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Copyright | © 2021 Wiley Periodicals LLC. |
Topics |
- Cost-Benefit Analysis
- Early Detection of Cancer
- Humans
- Mass Screening
- Mouth Neoplasms
(diagnosis)
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