Rebound peripheral blastosis with subsequent remission during remission induction in a patient with acute promyelocytic leukemia.

Abstract	A patient with acute promyelocytic leukemia manifested peripheral blastosis with 50% peripheral blasts and an absolute blast count of 10,000/microliter 2 weeks after the start of induction chemotherapy. The subsequent disappearance of the peripheral and marrow blasts without further chemotherapy was noticed, and complete remission was achieved on day 25 of chemotherapy. The histologic and clinical implications of this phenomenon are discussed.
Authors	R Amato, H Kantarjian, R Walters, M Keating
Journal	Cancer (Cancer) Vol. 61 Issue 4 Pg. 650-3 (Feb 15 1988) ISSN: 0008-543X [Print] United States
PMID	3422175 (Publication Type: Case Reports, Journal Article)
Chemical References	Cytarabine Vincristine Prednisone
Topics	Adult Antineoplastic Combined Chemotherapy Protocols (therapeutic use) Bone Marrow (pathology) Cytarabine (administration & dosage) Female Follow-Up Studies Hematopoietic Stem Cells (drug effects) Humans Leukemia, Myeloid, Acute (blood, drug therapy, pathology) Prednisone (administration & dosage) Vincristine (administration & dosage)

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