Abstract | BACKGROUND: METHODS: A prospective cohort study was performed in 53 patients who recovered from COVID-19 and visited our tertiary hospital. Subjective olfactory function was evaluated using the 11-point Likert scale (0-10) and the Korean version of the Questionnaire of Olfactory Disorders (QOD). Objective olfactory function was evaluated using Cross-Cultural Smell Identification Test (CC-SIT). Confirmed patients were followed up after 2 months of olfactory training. RESULTS: The median, interquartile range (Q1-Q3) score of subjective olfactory function significantly deteriorated in patients with olfactory dysfunction (OD) than in those without OD, even after 3 months of onset (11-point Likert scale, 8, 6-9 vs. 10, 10-10; short version of QOD-negative statements, 19, 16-21 vs. 21, 21-21; QOD-visual analogue scale, 7, 1-13 vs. 0, 0-0; all P < 0.001). However, the objective olfactory function was not significantly different between the two groups (median, interquartile range; 11, 9-11 vs. 11, 9-11, P = 0.887). The percentage of patients with objective hyposmia (CC-SIT ≤ 10) was also not significantly different (47.4% vs. 40%, P = 0.762). OD in COVID-19 was normalized after 2 months of olfactory training in 70% of patients even after 3 months of olfactory impairment. CONCLUSION: Although subjective olfactory function is significantly decreased in the OD group, the objective olfactory function was not significantly different. Moreover, olfactory training is effective in COVID-19 patients with OD.
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Authors | Min Young Seo, Won Suk Choi, Seung Hoon Lee |
Journal | Journal of Korean medical science
(J Korean Med Sci)
Vol. 36
Issue 22
Pg. e161
(Jun 07 2021)
ISSN: 1598-6357 [Electronic] Korea (South) |
PMID | 34100564
(Publication Type: Journal Article)
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Copyright | © 2021 The Korean Academy of Medical Sciences. |
Topics |
- Adult
- COVID-19
(complications, diagnosis, virology)
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Olfaction Disorders
(etiology, pathology)
- Prospective Studies
- SARS-CoV-2
(isolation & purification)
- Severity of Illness Index
- Surveys and Questionnaires
- Tertiary Care Centers
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