Abstract | INTRODUCTION: MATERIALS AND METHODS: It was a hospital based, prospective, interventional study conducted on patients diagnosed as Benign essential blepharospasm (BEB), Meige syndrome (MS) and Hemifacial spasm (HFS) by oculoplastic surgeon at Oculoplasty department OPD, Tilganga Institute of Ophthalmology, from December 2018 to November 2019. After taking all standard precautions for botulinum toxin injections, 6 to 8 sites for injecting 2.5 to 5 IU of the toxin were given. All the patients were evaluated before and after injections according to Jankovic spasm grading and improvement in functional impairment scale and followed on one week, one month, three month and when the symptoms reappeared. RESULTS: A total of 43 cases which included 32 cases of Benign essential Blepharospasm, 9 Hemifacial spasm and 2 Meige syndrome. The mean Jankovic severity score was 3.51 ± 0.51 (range 3-4). The mean improvement in functional score was 2.60 ± 0.54 (range 1-3), was statistically significant (p-value <0.001).The effective period of injection was 130 ± 20.82 (93 - 189) days.38 patients had repeated injections after reappearance of symptoms. 4 patients had side effects of redness and hematoma at one site. CONCLUSION:
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Authors | Malita Amatya, Ben Limbu, Purnima Rajkarnikar Sthapit, Hom Bahadur Gurung, Rohit Saiju |
Journal | Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH
(Nepal J Ophthalmol)
Vol. 13
Issue 25
Pg. 40-49
(Jan 2021)
ISSN: 2091-0320 [Electronic] Nepal |
PMID | 33981096
(Publication Type: Journal Article)
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Copyright | © NEPjOPH. |
Chemical References |
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Topics |
- Blepharospasm
(drug therapy)
- Botulinum Toxins, Type A
- Facial Muscles
- Hemifacial Spasm
(drug therapy)
- Humans
- Prospective Studies
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