A patient with systemic lupus erythematosus presenting both central nervous system lupus and steroid induced psychosis.

Abstract

We describe a patient with systemic lupus erythematosus (SLE) who presented with both steroid induced psychosis and central nervous system (CNS) SLE at different times. The cerebrospinal fluid (CSF) immunoglobulin indices and electroencephalogram were found to be helpful and reliable for the correct diagnosis of both conditions. There have been no reports of patients with SLE who showed both steroid induced psychosis and CNS SLE, and our patient has provided substantial evidence that both conditions can occur in the same individual.

• Authors: S Hirohata, S Iwamoto, T Miyamoto, H Sugiyama, K Nakano, S Inokuma
• Journal: The Journal of rheumatology (J Rheumatol) Vol. 15 Issue 4 Pg. 706-10 (Apr 1988) ISSN: 0315-162X [Print] Canada
• PMID: 3397982 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulins
• Steroids
• Cyclophosphamide
• Prednisolone

Topics

• Adult
• Brain Diseases (etiology)
• Cyclophosphamide (therapeutic use)
• Female
• Humans
• Immunoglobulins (cerebrospinal fluid)
• Lupus Erythematosus, Systemic (cerebrospinal fluid, complications, drug therapy)
• Prednisolone (administration & dosage, adverse effects, therapeutic use)
• Psychoses, Substance-Induced (complications)
• Steroids (adverse effects)