Abstract | BACKGROUND: METHODS: One hundred fifty-two female patients with physical classification type I or II according to the American Society of Anesthesiologists undergoing thoracoscopic surgery were arbitrarily classified into two categories, either receiving sufentanil and dezocine-based PCIA (group C) or incorporating dexmedetomidine with sufentanil and dezocine-based PCIA (group D). The patients' global satisfaction degree, postoperative nausea and vomiting ( PONV), PCA bolus, rescue analgesia requirements, drug-related adverse effects, rest and coughing visual analogue scale (VAS) ratings, and Ramsay sedation scores (RSS) were measured at 6, 12, 24, 36 and 48 h after surgery. RESULTS: Compared with the C group, the patient satisfaction degree was significantly higher; pain scores at rest and coughing were significantly different at 6, 12, 24, 36 and 48 h postoperatively; less rescue analgesia and PCA bolus were required; and a lower incidence of PONV was found in the D group. There were non-significant trends for the sedation scores and drug-related adverse effects in both groups. CONCLUSIONS: TRIAL REGISTRATION: Chinese Clinical Trial Registry number, ChiCTR2000030429 . Registered on March 1, 2020.
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Authors | Qiongzhen Li, Haixia Yao, Meiying Xu, Jingxiang Wu |
Journal | Journal of cardiothoracic surgery
(J Cardiothorac Surg)
Vol. 16
Issue 1
Pg. 102
(Apr 21 2021)
ISSN: 1749-8090 [Electronic] England |
PMID | 33882970
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Analgesics, Non-Narcotic
- Analgesics, Opioid
- Bridged Bicyclo Compounds, Heterocyclic
- Tetrahydronaphthalenes
- Dexmedetomidine
- Sufentanil
- dezocine
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Topics |
- Adult
- Analgesia
(methods)
- Analgesia, Patient-Controlled
(adverse effects)
- Analgesics, Non-Narcotic
(therapeutic use)
- Analgesics, Opioid
(therapeutic use)
- Bridged Bicyclo Compounds, Heterocyclic
(administration & dosage)
- Dexmedetomidine
(administration & dosage)
- Female
- Humans
- Middle Aged
- Pain Management
- Pain Measurement
- Pain, Postoperative
(etiology, surgery)
- Patient Satisfaction
- Postoperative Period
- Sufentanil
(administration & dosage)
- Tetrahydronaphthalenes
(administration & dosage)
- Thoracoscopy
- Time Factors
- Treatment Outcome
- Visual Analog Scale
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