Efficacy of Electroacupuncture Combined with Tropisetron in Treating Carboprost Tromethamine-Induced Nausea and Vomiting during Cesarean Section under Lumbar Anesthesia.

Abstract

OBJECTIVE:

We evaluated the efficacy of electroacupuncture combined with tropisetron in treating carboprost tromethamine-induced nausea and vomiting during cesarean section under lumbar anesthesia.

METHODS:

A total of 264 patients aged 22-40 years were enrolled, who received carboprost tromethamine and suffered nausea and vomiting during cesarean section under lumbar anesthesia. The patients were divided randomly into the control group, electroacupuncture group, tropisetron group, and electroacupuncture + tropisetron group.

RESULTS:

Compared to the control group, the nausea and vomiting scores decreased at T3 in both the electroacupuncture and electroacupuncture + tropisetron groups, and decreased at T4 in the electroacupuncture group, tropisetron group, and electroacupuncture + tropisetron group; the motilin, gastrin, and 5-hydroxytryptamine (5-HT) levels decreased at T5 in the other 3 groups. Compared to the electroacupuncture + tropisetron group, the nausea and vomiting scores increased at T3 in the control and tropisetron groups, and increased at T4 in the other 3 groups; the motilin, gastrin, and 5-HT levels increased at T5.

CONCLUSIONS:

Our study suggested that electroacupuncture combined with tropisetron could effectively relieve carboprost tromethamine-induced nausea and vomiting during cesarean section under lumbar anesthesia. The effect was better than its single application, and the reduced 5-HT, motilin, and gastrin levels might be involved in the underlying mechanism.

• Authors: Lili Yu, Zhongyan Yao, Qianjie Wei, Min Qu, Qiang Yang, Yulin Chang
• Journal: Complementary medicine research (Complement Med Res) Vol. 28 Issue 6 Pg. 516-522 ( 2021) ISSN: 2504-2106 [Electronic] Switzerland
• Vernacular Title: Wirksamkeit der Elektroakupunktur in Kombination mit Tropisetron bei der Behandlung von Carboprost-Tromethamin-induzierter Übelkeit und Erbrechen während eines Kaiserschnitts in Spinalanästhesie.
• PMID: 33784688 (Publication Type: Journal Article, Randomized Controlled Trial)
• Copyright: © 2021 S. Karger AG, Basel.

Chemical References

• Antiemetics
• Drug Combinations
• Indoles
• Tromethamine
• Tropisetron
• Carboprost
• carboprost tromethamine

Topics

• Antiemetics (therapeutic use)
• Carboprost
• Cesarean Section
• Double-Blind Method
• Drug Combinations
• Electroacupuncture
• Female
• Humans
• Indoles (therapeutic use)
• Nausea (drug therapy, therapy)
• Pregnancy
• Tromethamine
• Tropisetron (therapeutic use)
• Vomiting (drug therapy, therapy)