PubMed database, Web of Science, and SCOPUS were searched from their inception until November 2019 for articles describing
osteoid osteoma. Demographic data, success rates, pre- and post-procedure VAS scores, and complications were recorded. A random-effects meta-analyses of the VAS
pain score at various time points were calculated.
RESULTS: For
radiofrequency ablation, VAS scores for
pain at pre-procedure, 24-48 h, and 3-6 months yielded cumulative
pain scores of 7.64 +/- 0.175, 0.78 +/- 0.186, and 0.02 +/- 0.0196, respectively. For
cryoablation, VAS scores at pre-procedure, 24-48 h, and 3-6 months yielded cumulative
pain scores of 8.46 +/- 0.549, 0.975 +/- 0.66, and 0.112 +/- 0.08, respectively. For
laser ablation, VAS scores at pre-procedure and 24-48 h yielded cumulative
pain scores of 4.94 +/- 1.42, and 0.506 +/- 0.268, respectively. For microwave ablation, VAS scores at pre-procedure, 24-48 h, and 3-6 months yielded cumulative
pain scores of 6.14 +/- 1.07, 1.636 +/- 1.215, and 0 +/- 0.0, respectively. All ablation methods resulted in significant immediate and lasting
pain reduction (p < 0.001). Technical and clinical success rates and major complications for RFA, microwave
ablation, laser ablation, and
cryoablation did not differ significantly. Overall recurrence of bone
pain at the same site occurred in 4.06% of all patients an average of 11 months post-procedure.
CONCLUSION: