[DRESS syndrome induced by sulfasalazine. Report of one case].

Abstract

DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is a severe, rare and potentially lethal idiosyncratic condition associated with the use of some drugs. Given its broad spectrum of presentation, clinical suspicion is essential for management, since it requires the immediate withdrawal of the culprit drug, support measures and the use of corticosteroids as the first line of treatment. We report a 24-year-old woman with a diagnosis of ulcerative colitis with joint involvement despite the use of infliximab, who presented symptoms, signs and laboratory compatible with DRESS syndrome on the third week after indicating sulfasalazine for her baseline disease.

• Authors: Edith Arce, Rodrigo Quera, Lilian Flores, Rodrigo Blamey
• Journal: Revista medica de Chile (Rev Med Chil) Vol. 148 Issue 8 Pg. 1213-1218 (Aug 2020) ISSN: 0717-6163 [Electronic] Chile
• Vernacular Title: Síndrome de DRESS inducido por sulfasalazina. ¿Consideramos esta reacción adversa grave al indicar el fármaco? Caso clínico.
• PMID: 33399789 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenal Cortex Hormones
• Antirheumatic Agents
• Sulfasalazine
• Infliximab

Topics

• Adrenal Cortex Hormones
• Antirheumatic Agents (adverse effects)
• Drug Hypersensitivity Syndrome (diagnosis, etiology)
• Eosinophilia (chemically induced)
• Female
• Humans
• Infliximab
• Sulfasalazine (adverse effects)
• Young Adult