Investigation of deep-seated brain tumor treatment based on Tehran research reactor new boron neutron capture therapy facility.

Abstract

AIM:

The main objective of this study is to evaluate the new proposed boron neutron capture therapy (BNCT) neutron beam based on the use of Tehran Research Reactor medical room to treat deep-seated brain tumors.

MATERIAL AND METHODS:

The Snyder head phantom has been simulated through the MCNPX Monte Carlo code to calculate different dose profiles and desired medical merits. The simulation consists of the full geometry of new beamline and the phantom.

RESULTS:

The medical merits related to the new proposed BNCT beamline have a good agreement with other facilities, which indicates the potential use of this new beam for treatment of deep-seated brain tumors.

CONCLUSION:

The obtained results show the capability of the new setup to treat deep-seated brain tumor, which was located up to ~5 cm of the skin surface.

• Authors: Mohadeseh Golshanian, Yaser Kasesaz
• Journal: Journal of cancer research and therapeutics (J Cancer Res Ther) 2020 Oct-Dec Vol. 16 Issue 6 Pg. 1454-1458 ISSN: 1998-4138 [Electronic] India
• PMID: 33342812 (Publication Type: Evaluation Study, Journal Article)

Topics

• Boron Neutron Capture Therapy (methods)
• Brain Neoplasms (diagnostic imaging, radiotherapy)
• Computer Simulation
• Head (diagnostic imaging)
• Humans
• Iran
• Monte Carlo Method
• Phantoms, Imaging
• Radiotherapy Planning, Computer-Assisted (instrumentation, methods)