Anesthetic Management of Living-Donor Renal Transplantation in a Patient With Epstein Syndrome Using Rotational Thromboelastometry: A Case Report.

Abstract

Epstein syndrome is a myosin heavy chain 9 (MYH9)-related disorder characterized by hearing loss and macrothrombocytopenia with renal failure, which usually requires platelet transfusion during surgery. We report the case of a 22-year-old man who underwent living-donor renal transplantation without platelet transfusion using rotational thromboelastometry (ROTEM) monitoring. His intraoperative laboratory coagulation findings were a platelet count of 28-31 × 10/L based on microscopy and fibrinogen of 256 mg/dL. However, his extrinsic pathway evaluations by ROTEM were normal. The estimated blood loss during the operation was 150 mL, and the patient showed no bleeding complications without platelet transfusion.

• Authors: Midoriko Higashi, Keizo Kaku, Yasuhiro Okabe, Ken Yamaura
• Journal: A&A practice (A A Pract) Vol. 14 Issue 13 Pg. e01350 (Nov 2020) ISSN: 2575-3126 [Electronic] United States
• PMID: 33236872 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anesthetics

Topics

• Adult
• Anesthetics
• Hearing Loss, Sensorineural
• Humans
• Kidney Transplantation
• Living Donors
• Male
• Thrombelastography
• Thrombocytopenia (congenital)
• Young Adult