Ehlers-Danlos Syndromes (EDS) and related Hypermobility Spectrum Disorders (HSD) are debilitating connective tissue disorders that feature a prominent
pain component for which there are limited therapeutic options for
pain management. Consequently, many patients try various non-prescribed treatments, including complementary and
alternative therapies that have not been well studied in the EDS/HSD patient population. We surveyed over 500 individuals through the EDS Society who reported having been diagnosed with EDS or HSD to ascertain what complementary and
alternative therapies were used and their reported effectiveness in alleviating
pain and improving quality of life. Specifically, we focused on the use of traditional Chinese
therapies, herbal medications, and marijuana. The most commonly reported
therapies, used by 70-92% of participants, were non-steroidal anti-inflammatory drugs,
acetaminophen,
opioids, and
physical therapy.
Therapies rated by participants as most efficacious were
opioids,
physical therapy, and marijuana with 10-24% of those using these
therapies rating them as extremely helpful. Patient-initiated complementary
therapy use in EDS/HSD patients is widespread at 56%.
Complementary therapies were largely utilized by EDS/HSD patients with higher reported
pain levels. Providers caring for EDS/HSD patients should be aware of these data showing broad usage of predominantly non-prescribed
therapies and be prepared to consider such usage in working collaboratively with these patients to develop comprehensive treatment plans to manage their
chronic pain complications.