Abstract | OBJECTIVES: METHODS: We followed PRISMA guidelines to perform a systematic identification of relevant publications in the literature on four academic databases: MEDLINE, Scopus, EMBASE, and CENTRAL. RESULTS: Out of 1845 records, we included data from 15 articles including 420 970 participants in this review. Our systematic review presents a 2b level of evidence suggesting a higher duration of hospital stay, Charlson comorbidity index score, and mortality rate for patients with COPD and anemia than for patients with COPD without anemia. The meta-analysis revealed a moderate effect increase in the mean duration of hospital stay (Hedge's g, 0.55), Charlson comorbidity index (0.68), and mortality rate (0.49) in patients with COPD and anemia as compared to those in patients with COPD without anemia. CONCLUSION: The current systematic review and meta-analysis provide evidence regarding the detrimental consequences of anemia on the morbidity and mortality of patients with COPD.
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Authors | Yan Xu, Tao Hu, Huizhen Ding, Rui Chen |
Journal | Expert review of respiratory medicine
(Expert Rev Respir Med)
Vol. 14
Issue 12
Pg. 1267-1277
(12 2020)
ISSN: 1747-6356 [Electronic] England |
PMID | 32869670
(Publication Type: Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't, Systematic Review)
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Topics |
- Aged
- Anemia
(complications, epidemiology)
- Comorbidity
- Female
- Humans
- Male
- Middle Aged
- Pulmonary Disease, Chronic Obstructive
(complications, mortality)
- Quality of Life
- Risk Factors
- Survival Rate
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