The Treatment Models for Adenoviral Keratoconjunctivitis in the Childhood Population.

Abstract

Purpose: To examine the effects of treatments performed on children with adenoviral conjunctivitis.Methods: 50 children with Adenoviral keratoconjunctivitis (AK) were evaluated. Patients were divided into four groups according to the medical treatment agents that were used previously. AK symptoms were clinically scored and analyzed. The diagnosis of all children was confirmed by an in-office lateral flow immunoassay.Results: Fifty patients with AK were included in the study. 24 (48%) were female and 26 (52%) were male. The mean age was 12.88 ± 2.66 (8-17). In PVP-I groups clinical findings shows faster improvement than other groups (p < .05).Conclusions: Conjunctival irrigation with 2.5% PVP-I is very effective for the treatment of adenoviral conjunctivitis in childhood. Ganciclovir ophthalmic gel 0.15% increases the effect of 2.5% PVP-I on AK, but this was not statistically significant.

• Authors: Sinan Bekmez, Erdem Eris
• Journal: Ocular immunology and inflammation (Ocul Immunol Inflamm) Vol. 29 Issue 7-8 Pg. 1627-1632 (Nov 17 2021) ISSN: 1744-5078 [Electronic] England
• PMID: 32643975 (Publication Type: Journal Article)

Chemical References

• Anti-Infective Agents, Local
• Antiviral Agents
• Ophthalmic Solutions
• Povidone-Iodine
• Ganciclovir

Topics

• Adenovirus Infections, Human (diagnosis, drug therapy, virology)
• Administration, Ophthalmic
• Adolescent
• Anti-Infective Agents, Local (therapeutic use)
• Antiviral Agents (therapeutic use)
• Child
• Drug Synergism
• Eye Infections, Viral (diagnosis, drug therapy, virology)
• Female
• Ganciclovir (therapeutic use)
• Humans
• Immunoassay (methods)
• Keratoconjunctivitis (diagnosis, drug therapy, virology)
• Male
• Ophthalmic Solutions
• Povidone-Iodine (therapeutic use)
• Retrospective Studies