Observation on the effects of 595- nm pulsed dye laser and 755- nm long-pulsed alexandrite laser on sequential therapy of infantile hemangioma.

Abstract

BACKGROUND:

Infantile hemangioma (IH) can lead to severe complications. The 595-nm pulsed dye laser is poorly effective on thick and deep IH. Long-pulsed alexandrite laser has the proper wavelength of 755 nm and a relatively deep penetration. Thus, this may be a safe and effective treatment method for relatively deep or thick IH.

AIMS AND OBJECTIVES:

This study aims to determine whether 595-nm pulsed dye laser and 755-nm long-pulsed alexandrite laser in sequential therapy are safer and more effective for relatively deep or thick hemangioma.

MATERIALS AND METHODS:

This was a prospective study. A total of 194 infantile IH patients (thickness greater than 2 mm and less than 8 mm) were randomly divided into two groups: control group (treated using 595-nm pulsed dye laser) and experimental group (treated by sequential therapy with 755-nm long-pulsed alexandrite laser and 595-nm dye laser).

RESULTS:

The control group had a total effective rate of 36.1%, while the experimental group had a total effective rate of 76.3%. Enumeration data were compared by X2 -test. The results were considered statistically significant at P < .05.

CONCLUSION:

Sequential therapy with 755-nm pulsed dye laser and 595-nm long-pulsed alexandrite laser is a safe and effective treatment approach for relatively deep or thick hemangioma.

• Authors: Wan-Wan Jin, Yi Tong, Jian-Ming Wu, He-He Quan, Yu Gao
• Journal: Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology (J Cosmet Laser Ther) Vol. 22 Issue 3 Pg. 159-164 (Apr 02 2020) ISSN: 1476-4180 [Electronic] England
• PMID: 32588671 (Publication Type: Journal Article, Randomized Controlled Trial)

Topics

• Hemangioma (surgery)
• Hemangioma, Capillary (surgery)
• Humans
• Laser Therapy
• Lasers, Dye (adverse effects)
• Lasers, Solid-State (adverse effects)
• Prospective Studies
• Treatment Outcome