Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine.

Abstract

Novel coronavirus disease (COVID-19) is a highly contagious disease caused by severe acute respiratory distress syndrome coronavirus-2 that has resulted in the current global pandemic. Currently, there is no available treatment proven to be effective against COVID-19, but multiple medications, including hydroxychloroquine (HCQ), are used off label. We report the case of a 60-year-old woman without any cardiac history who developed right bundle brunch block and critically prolonged corrected electrocardiographic QT interval (QTc 631 ms) after treatment for 3 days with HCQ, which resolved on discontinuation of the medication. This case highlights a significant and potentially life-threatening complication of HCQ use.

• Authors: Rosmonaliza Asli, Muhammad Syafiq Abdullah, Pui Lin Chong, Dhiya Metussin, Riamiza Natalie Momin, Babu Ivan Mani, Vui Heng Chong
• Journal: The American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 103 Issue 1 Pg. 79-82 (07 2020) ISSN: 1476-1645 [Electronic] United States
• PMID: 32383430 (Publication Type: Journal Article)

Chemical References

• Hydroxychloroquine

Topics

• Betacoronavirus
• Brunei
• Bundle-Branch Block (chemically induced)
• COVID-19
• Coronavirus Infections (drug therapy)
• Echocardiography
• Female
• Humans
• Hydroxychloroquine (adverse effects, therapeutic use)
• Long QT Syndrome (chemically induced)
• Middle Aged
• Pandemics
• Pneumonia, Viral (drug therapy)
• SARS-CoV-2