Dual-energy CT to differentiate gallbladder polyps: cholesterol versus adenomatous.

Abstract

BACKGROUND:

Dual-energy computed tomography (DE-CT) scans were acquired to identify cholesterol and adenomatous gallbladder (GB) polyps, which have not been well evaluated before surgery.

PURPOSE:

To evaluate the DE-CT findings of GB polyps 1.0-2.0 cm in size and differentiate between cholesterol and adenomatous polyps.

MATERIAL AND METHODS:

Forty-six patients with GB polyps were surgically treated from December 2017 to December 2019 and divided into two groups according to their postoperative pathologic results: a cholesterol group with 26 patients and an adenomatous group with 20 patients. All of these patients underwent DE-CT imaging with tube voltages of 80 kVp and 140 kVp within two weeks before surgery. Mean attenuation values were measured for every GB polyp at 80/140 kVp and at 40/140 keV. The mean attenuation value changes between 140 kVp and 80 kVp (MAVC140-80 kVp) and mean attenuation value changes between 100 keV and 40 keV (MAVC100-40 keV) were calculated.

RESULTS:

The CT image parameters of all 46 patients with GB polyps were analyzed. There were significant differences in MAVC140-80 kVp and MAVC100-40 keV between cholesterol and adenomatous polyps (P <0.05); these values were positive for cholesterol polyps and negative for adenomatous polyps.

CONCLUSION:

The unique energy spectrum information provided by DE-CT scans is helpful in differentiating between cholesterol and adenomatous polyps 1.0-2.0 cm in size.

• Authors: Sheng Nan Yin, Jing Chi, Li Liu, Ning Ding, Yi Ding Ji, Jian Mao Yuan
• Journal: Acta radiologica (Stockholm, Sweden : 1987) (Acta Radiol) Vol. 62 Issue 2 Pg. 147-154 (Feb 2021) ISSN: 1600-0455 [Electronic] England
• PMID: 32295387 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Cholesterol

Topics

• Adenomatous Polyps (diagnostic imaging, surgery)
• Adult
• Aged
• Cholecystectomy
• Cholesterol
• Diagnosis, Differential
• Female
• Gallbladder (diagnostic imaging, surgery)
• Gallbladder Neoplasms (diagnostic imaging, surgery)
• Humans
• Male
• Middle Aged
• Polyps (diagnostic imaging, surgery)
• Radiographic Image Interpretation, Computer-Assisted (methods)
• Radiography, Dual-Energy Scanned Projection (methods)
• Reproducibility of Results
• Retrospective Studies
• Tomography, X-Ray Computed (methods)
• Young Adult