Imiquimod-associated erythema multiforme.

Abstract

Patients with multiple actinic keratoses are frequently treated with topical agents such as imiquimod, an immune-response modifying agent. Adverse effects associated with imiquimod therapy are mainly limited to the application site and include erythema, crusting, scaling and ulceration. Systemic adverse reactions, such as erythema multiforme are rare. Here we report a case of a 77- years old patient that developed erythema multiforme after treatment of actinic keratoses with imiquimod. Cessation of imiquimod and treatment with local corticosteroids led to rapid regression of erythema multiforme lesions. Residual actinic keratoses were treated with cryotherapy.

• Authors: Katarina Trčko
• Journal: Acta dermatovenerologica Alpina, Pannonica, et Adriatica (Acta Dermatovenerol Alp Pannonica Adriat) Vol. 29 Issue 1 Pg. 47-49 (03 2020) ISSN: 1581-2979 [Electronic] Slovenia
• PMID: 32206824 (Publication Type: Case Reports, Journal Article)

Chemical References

• Imiquimod

Topics

• Aged
• Drug Eruptions (etiology, pathology)
• Erythema Multiforme (chemically induced, pathology)
• Humans
• Imiquimod (adverse effects)
• Male