[A Case of Multimodality Treatment Including Carbon Ion Radiotherapy to Multiple Distant Lymph Node Metastasis after a Surgery for Sigmoid Cancer].

Abstract

We reported a case of a 30s woman who underwent Hartmann's surgery for sigmoid cancer. Her pathological stage was Stage Ⅳ(pT4b, N1b, M1b[liver and lung]). Postoperatively, 10 courses of systemic chemotherapy with FOLFOX plus cetuximab( Cmab)or bevacizumab(Bmab)were administered. After the chemotherapy, partial liver dissection and radiofrequency ablation(RFA)for multiple liver metastasis were performed. After 2 years of systemic chemotherapy with FOLFIRI plus ramucirumab(RAM), no liver or lung metastasis was observed; however, left supraclavicular lymph node and para-aortic lymph node metastases existed and gradually increased. For the purpose of local control, the para-aortic lymph node metastasis was treated with cervical dissection and carbon ion radiotherapy. Therefore, carbon ion radiotherapy was a useful treatment for local control.

• Authors: Masakazu Miyake, Mamoru Uemura, Takeshi Kato, Takuya Hamakawa, Sakae Maeda, Naoki Hama, Kazuhiro Nishikawa, Atsushi Miyamoto, Michihiko Miyazaki, Motohiro Hirao, Tsuyoshi Ishikawa, Shigeru Yamada, Mitsugu Sekimoto
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 46 Issue 13 Pg. 1978-1980 (Dec 2019) ISSN: 0385-0684 [Print] Japan
• PMID: 32157032 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols
• Female
• Heavy Ion Radiotherapy
• Humans
• Lymph Node Excision
• Lymph Nodes
• Lymphatic Metastasis
• Sigmoid Neoplasms (therapy)