Abstract | PURPOSE: Topical cosmetic agents if correctly prescribed and used may improve outcomes in acne therapy. The aim of this study was to assess the efficacy and tolerability of a new daily cosmetic regimen in the treatment of mild facial acne. PATIENTS AND METHODS: A multicenter, prospective, observational, clinical study was conducted on 91 adult patients with mild acne. Subjects were instructed to apply a fluid containing Licochalcone A/ Salicylic acid/ L-Carnitine in the morning and a cream with Licochalcone A/Hydroxy-Complex 10% at bedtime for 8 weeks. The efficacy was clinically evaluated by Global Acne Grading System (GAGS) score and by comedones/papules lesions count and by instrumental assessment (SebutapeTMand Reveal Photo Imager/VISIA-CR™ imaging) at baseline, at 4 and 8 weeks. RESULTS: At 4 weeks a statistically significant reduction from baseline of GAGSwas observed. In addition, the mean total count of comedones and papules was significantly reduced by 41% and 45%, respectively, from baseline along with a significant reduction of mean sebum of 47%. At 8 weeks, a further statistically significant reduction from baseline of GAGS, total count of comedones and papules (64% and 71%, respectively), along with an additional sebum reduction of about 52% was also recorded. CONCLUSION:
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Authors | Federica Dall'Oglio, Gabriella Fabbrocini, Aurora Tedeschi, Marianna Donnarumma, Paolo Chiodini, Giuseppe Micali |
Journal | Clinical, cosmetic and investigational dermatology
(Clin Cosmet Investig Dermatol)
Vol. 12
Pg. 961-967
( 2019)
ISSN: 1178-7015 [Print] New Zealand |
PMID | 32099436
(Publication Type: Journal Article)
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Copyright | © 2019 Dall’Oglio et al. |