Effects of endolymphatic sac decompression combined with posterior tympanotomy with local steroids for intractable Meniere's disease.

Abstract

Background: Endolymphatic sac decompression surgery (ESDS) is commonly used for intractable Meniere's disease, but its effect remains controversial because of the low rate of vertigo control.Objectives: In the present study, we examined ESDS combined with posterior tympanotomy with local steroids as a new therapeutic strategy for intractable Meniere's disease.Materials and methods: This retrospective study enrolled 19 patients with Meniere's disease using ESDS combined with posterior tympanotomy with local steroids between 2015 and 2018. Postoperatively we recorded and evaluated changes in vertigo attack frequency and hearing level.Results: Vertigo episodes decreased from 3.6 ± 3.2 times preoperatively to 0.2 ± 0.5 times postoperatively, with 89.5% complete vertigo control rate. Mean PTA decreased from 40.5 ± 21.3 dB to 39.5 ± 17.5 dB postoperatively, with 21.1% improvement rate.Conclusions and significance: The present findings suggest that ESDS combined with posterior tympanotomy with local steroids could improve clinical results of hearing as well as vertigo control for intractable Meniere's disease.

• Authors: Jia Xu, Haijin Yi, Xin Li, Wenjing Chen, Juanjuan Gao
• Journal: Acta oto-laryngologica (Acta Otolaryngol) Vol. 140 Issue 4 Pg. 258-261 (Apr 2020) ISSN: 1651-2251 [Electronic] England
• PMID: 32031482 (Publication Type: Journal Article)

Chemical References

• Glucocorticoids
• Dexamethasone

Topics

• Adult
• Aged
• Decompression, Surgical (methods)
• Dexamethasone (administration & dosage)
• Endolymphatic Sac (surgery)
• Female
• Glucocorticoids (administration & dosage)
• Humans
• Male
• Meniere Disease (drug therapy, surgery)
• Middle Aged
• Retrospective Studies
• Tympanic Membrane (surgery)
• Vertigo (drug therapy, surgery)