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Improved Injection Technique of Ethanol for Morton's Neuroma.

AbstractBACKGROUND:
Morton's neuroma is a common cause of forefoot pain. Various conservative methods (injections of various pharmacologic agents) have been published with an outcome of 6%-75% success rate (free of pain in daily life) per injection. The aim of the present study was to assess the outcome of an improved localization technique, a higher dosage, and a higher percentage of ethanol.
METHODS:
Using fluoroscopic and electroneurographic guidance, 2.5 mL of 70% ethanol were injected into 33 feet with a magnetic resonance imaging (MRI)-verified neuroma. We evaluated patients at up to 5-year follow-up.
RESULTS:
A "success rate" of more than 82% per single injection (defined as free of pain in daily life) was achieved and no recurrence was seen over 5 years. All scores (visual analog scale; Short Form-36 subscales, American Orthopaedic Foot & Ankle Society ankle-hindfoot score) showed significant improvement (P < .0001). Mean 1.2 injections were necessary. No significant side effects were seen. However, some mild pain persisted in some patients who participated in sports.
CONCLUSION:
The injection of 2.5 mL of 70% ethanol under fluoroscopic and electroneurographic guidance was a safe method for the treatment of MRI-verified Morton's neuromas. Combining the effect of a higher percentage of alcohol and a higher dosage and an improved localization technique resulted in a high rate of patients without pain.
LEVEL OF EVIDENCE:
Level IV, cases series, prospective.
AuthorsChristof Pabinger, Isabella Malaj, Harald Lothaller, Elena Samaila, Bruno Magnan
JournalFoot & ankle international (Foot Ankle Int) Vol. 41 Issue 5 Pg. 590-595 (05 2020) ISSN: 1944-7876 [Electronic] United States
PMID32013586 (Publication Type: Journal Article)
Chemical References
  • Ethanol
Topics
  • Adult
  • Aged
  • Ethanol (administration & dosage)
  • Female
  • Fluoroscopy
  • Humans
  • Injections, Intralesional (methods)
  • Male
  • Middle Aged
  • Morton Neuroma (drug therapy)
  • Prospective Studies

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